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SAUDI
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South America
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Nano™ 2nd Gen
embecta helps you correctly inject your insulin with innovative pen needle technology
- Overview
Did you know that how insulin is injected can be critical to help obtain the full benefits of the medication?1 A recent study showed that people with diabetes were making at least 1 mistake in how they inject insulin. The most common mistake was using too much force against the skin when injecting.2* This can result in accidentally injecting into the muscle layer, which can make an injection more painful and lead to insulin not working as it should.1,3
Contoured Base
Nano™ 2nd Gen 4mm Pen Needles have a unique contoured needle base that distributes forces across the skin surface, compensating for the force used to inject and allowing for less bruising and reduced risk of intramuscular injection.3,4
Confidence
Nano™ 2nd Gen 4mm Pen Needles have ultra-thin wall technology to increase the flow of insulin so less thumb pressure is needed to push the pen button, making it easier for you to give the injection and giving you confidence that you have received the full dose of insulin.5§
Comfort
The NanoTM 2nd Gen 4mm needle with 5-bevel tip provided more comfortable and less painful injections.6¶
Ease of Use
Nano™ 2nd Gen 4mm Pen Needles have an ergonomic design proven to make them easier to use from attachment through disposal.6#
Single Use
Use a new pen needle every time you inject. Pen needles are recommended to be used only once and are no longer sterile after that.1
Compatibility
NanoTM 2nd Gen 4mm Pen Needles are compatible with widely used pen injection devices, so even if your treatment regimen changes, you wonʼt have to change your choice of pen needle.7
*Results from a patient survey.
§ Ultra-thin wall was introduced as an ISO standard for inner wall diameter in 2016.
¶ Patients were aware of the pen needle they were using.
# 226 patients with diabetes on insulin treatment were studied with a 150 mm visual analog scale (mean scores of>0 mm; clinically significant difference of ≥5 mm). Nano™ 2nd Gen demonstrated superiority vs. all comparator groups combined for overall ease of use (P <0.05)(Mean 19.9 mm, 95% CI, +13.8 to +25.9 mm).
1. Frid AH, et al. New Insulin Delivery Recommendations. Mayo Clinic Proceedings. 2016;91(9):1231–1255.
2. Bari B, Corbeil MA, Farooqui H, et al. Insulin injection practices in a population of Canadians with diabetes: an observational study. Diabetes Ther. 2020;11(11):2595-2609.
3. Klonoff DC, Berard L, Franco DR, et al. Advance Insulin Injection Technique and Education with FITTER Forward Expert Recommendations. Mayo Clin Proc. 2025; 100(4):682-699.
4. Rini CR, Roberts BC, Morel D, et al. Evaluating the Impact of Human Factors and Pen Needle Design on Insulin Pen Injection. J Diabetes Sci Technol. 2019;13(3):533-545.
5. Aronson R, Gibney MA, Oza K, et al. Insulin pen needles: effects of extra-thin wall needle technology on preference, confidence, and other patient ratings. Clin Ther. 2013;35(7):923-933.
6. Hirsch L, Gibney M, Berube J, Manocchio J. Impact of a modified needle tip geometry on penetration force as well as acceptability, preference, and perceived pain in subjects with diabetes. J Diabetes Sci Technol. 2012;6(2):328-335.
7. Pen Needle Compatibility Status Summary with Diabetes Care & Non-Diabetes Drug Delivery Devices - Document Number: 149OTH-0004-20 Y – 2025-11-18.