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BD Nano™ 4mm
embecta is committed to helping patients with diabetes deliver their insulin correctly.
- Overview
- Products & Accessories
Despite your best efforts to educate patients around proper injection technique, it has been shown that most patients inject their insulin using a wide range of techniques, which can impact the correct delivery of insulin.1,2« With our pen needle technology, embecta is committed to helping patients correctly deliver their insulin.
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Accuracy
The BD Nano™ 4mm Pen Needle helps to reduce risk of intramuscular injection compared to needles 6mm and longer.3*
Comfort
The BD Nano™ 4mm Pen Needle can significantly help reduce pain during injection compared to larger and longer pen needles.4† The 5-bevel needle tip can bring a more comfortable and less painful injection.5^
Confidence
The BD Nano™ 4mm x 32G Pen Needle has ultra-thin wall technology, the highest inner diameter ISO standard for its category, and studies have shown that the increased flow of insulin results in greater ease of use and increased confidence that the complete dose has been delivered.6,7 ¥
Compatibility
BD Nano™ 4mm Pen Needles are compatible with widely used pen injection devices, so even if your regimen changes, you won’t have to change your choice of pen needle.8
Single Use
Recommend the use of a new pen needle every time your patients inject. Pen needles are recommended to be used only once and are no longer sterile after that. There is an association between needle reuse and injection pain or bleeding.1
«N = 230 patients with diabetes across Canada. Participants answered a survey as part of the cross-sectional observational behavioral study. BD helped fund this study.
*IM risk was estimated based on 90- or 45-degree insertion. Skin surface to muscle depth was measured by ultrasound. No actual injections were performed.
†Relative injection pain was evaluated via a 150 mm/VAS scale. P<0.02; clinical significance is indicated by 10 mm difference in the VAS scale.
^Compared to 3-bevel pen needles; 86 patients with diabetes participated in a randomized, non-inferiority crossover trial. During the blinded portion of the study there was no difference in pain; during the non-blinded portion of the study there was statistical difference, P<0.01.
¥198 patients with diabetes were included in this prospective, multicenter, randomized, open-label, 2- period, crossover study to evaluate differences in perceived thumb force and in confidence that the full dose of insulin was delivered, between the participants’ usual pen needle (PN) and the corresponding extra-thin wall (XTW) pen needle while using a manually operated insulin pen. Both outcomes were considered statistically significant if the 95% confidence interval (CI) for the mean VAS score was either positive (XTW preferred) or negative (current PN preferred). Significant differences favoring XTW pen needles were seen for perceived thumb force and confidence that the full dose was delivered by 28.4 mm (95% CI, 23.7-33.2), and 24.4 mm (95% CI, 19.7 – 29.1), respectively; (all, P < 0.001).
1. Frid AH, et al. New Insulin Delivery Recommendations. Mayo Clinic Proceedings. 2016;91(9):1231–1255
2. Bari B, Corbeil MA, Farooqui H, et al. Insulin injection practices in a population of Canadians with diabetes: an observational study. Diabetes Ther. 2020;11(11):2595-2609.
3. Gibney MA, Arce CH, Byron KJ, Hirsch LJ. Skin and subcutaneous adipose layer thickness in adults with diabetes at sites used for insulin injections: implications for needle length recommendations. Curr Med Res Opin. 2010;26(6):1519-1530
4. Hirsch LJ, Gibney MA, Albanese J, et al. Comparative glycemic control, safety, and patient ratings for a new 4 mm x 32G insulin pen needle in adults with diabetes. Curr Med Res Opin. 2010;26(6):1531-1541.
5. Hirsch L, Gibney M, Berube J, Manocchio J. Impact of a modified needle tip geometry on penetration force as well as acceptability, preference, and perceived pain in subjects with diabetes. J Diabetes Sci Technol. 2012;6(2):328-335
6. Stainless steel needle tubing for the manufacture of medical devices —requirements and test methods. ISO 9626. 2016.
7. Aronson R, Gibney MA, Oza K, et al. Insulin pen needles: effects of extra-thin wall needle technology on preference, confidence, and other patient ratings. Clin Ther. 2013;35(7):923-933.
8. BD Compatibility Confirmation for Pen Needles and Pen Injector Manufacturers. 149-OTH-0004-20, Rev S. February 2021.
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embecta, formerly part of BD. BD is the manufacturer of the advertised products.